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| 02.02.2022 | 14:30 | GS Arconatese 1926 | - | AC Crema | 0:1 | |
| 14:30 | US Ciserano | - | AC Pontisola | 5:3 | ||
| 14:30 | US Folgore Caratese | - | Legnano | 1:1 | ||
| 14:30 | Franciacorta | - | USD Casatese | 1:5 | ||
| 14:30 | AC Leon | - | Brusaporto | 1:3 | ||
| 14:30 | Real Calepina | - | Olginatese | 0:0 | ||
| 14:30 | Sona | - | SG City Nova | 1:0 | ||
| 14:30 | USD Caravaggio | - | US Breno | 1:0 | ||
| 14:30 | Vis Nova Giussano | - | Castellanzese | 2:2 | ||
| 02.03.2022 | 14:30 | Villa d'Almè | - | AC Calvina Sport | 2:2 |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SG City Nova | 21 | 13 | 4 | 4 | 38:20 | 18 | 43 |
| 2 |
|
AC Calvina Sport | 21 | 11 | 6 | 4 | 35:22 | 13 | 39 |
| 3 |
|
Brusaporto | 21 | 10 | 7 | 4 | 38:29 | 9 | 37 |
| 4 |
|
Legnano | 21 | 11 | 4 | 6 | 31:26 | 5 | 37 |
| 5 |
|
USD Casatese | 21 | 10 | 6 | 5 | 43:28 | 15 | 36 |
| 6 |
|
GS Arconatese 1926 | 21 | 9 | 8 | 4 | 32:23 | 9 | 35 |
| 7 |
|
US Folgore Caratese | 21 | 9 | 7 | 5 | 35:30 | 5 | 34 |
| 8 |
|
US Ciserano | 21 | 8 | 9 | 4 | 31:26 | 5 | 33 |
| 9 |
|
US Breno | 21 | 8 | 8 | 5 | 35:26 | 9 | 32 |
| 10 |
|
Sona | 21 | 7 | 6 | 8 | 29:33 | -4 | 27 |
| 11 |
|
Franciacorta | 21 | 6 | 9 | 6 | 38:46 | -8 | 27 |
| 12 |
|
AC Crema | 21 | 6 | 6 | 9 | 23:26 | -3 | 24 |
| 13 |
|
Olginatese | 21 | 5 | 9 | 7 | 24:29 | -5 | 24 |
| 14 |
|
Castellanzese | 21 | 6 | 3 | 12 | 27:33 | -6 | 21 |
| 15 |
|
AC Pontisola | 21 | 4 | 9 | 8 | 28:32 | -4 | 21 |
| 16 |
|
Real Calepina | 21 | 5 | 6 | 10 | 20:21 | -1 | 21 |
| 17 |
|
AC Leon | 21 | 5 | 5 | 11 | 27:46 | -19 | 20 |
| 18 |
|
Vis Nova Giussano | 21 | 6 | 2 | 13 | 35:45 | -10 | 20 |
| 19 |
|
USD Caravaggio | 21 | 4 | 7 | 10 | 27:41 | -14 | 19 |
| 20 |
|
Villa d'Almè | 21 | 3 | 7 | 11 | 22:36 | -14 | 16 |
| Ascenso | |
| Playoff | |
| Permanencia | |
| Descenso |
