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| 09.04.2022 | 15:00 | SG City Nova | - | Olginatese | 2:0 | |
| 15:00 | Vis Nova Giussano | - | US Folgore Caratese | 0:1 | ||
| 10.04.2022 | 15:00 | Brusaporto | - | AC Calvina Sport | 3:1 | |
| 15:00 | Castellanzese | - | US Breno | 1:1 | ||
| 15:00 | US Ciserano | - | USD Caravaggio | 4:1 | ||
| 15:00 | Legnano | - | AC Crema | 3:1 | ||
| 15:00 | AC Leon | - | Real Calepina | 4:3 | ||
| 15:00 | AC Pontisola | - | USD Casatese | 0:0 | ||
| 15:00 | Sona | - | GS Arconatese 1926 | 0:1 | ||
| 15:00 | Villa d'Almè | - | Franciacorta | 6:1 |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SG City Nova | 32 | 19 | 7 | 6 | 60:34 | 26 | 64 |
| 2 |
|
Brusaporto | 32 | 16 | 9 | 7 | 54:39 | 15 | 57 |
| 3 |
|
Legnano | 32 | 16 | 8 | 8 | 43:36 | 7 | 56 |
| 4 |
|
US Folgore Caratese | 32 | 16 | 8 | 8 | 51:39 | 12 | 56 |
| 5 |
|
AC Calvina Sport | 32 | 14 | 10 | 8 | 49:38 | 11 | 52 |
| 6 |
|
US Ciserano | 32 | 13 | 12 | 7 | 54:43 | 11 | 51 |
| 7 |
|
USD Casatese | 32 | 12 | 13 | 7 | 51:35 | 16 | 49 |
| 8 |
|
US Breno | 32 | 13 | 10 | 9 | 47:35 | 12 | 49 |
| 9 |
|
GS Arconatese 1926 | 32 | 13 | 10 | 9 | 48:40 | 8 | 49 |
| 10 |
|
Franciacorta | 32 | 12 | 11 | 9 | 62:66 | -4 | 47 |
| 11 |
|
AC Crema | 32 | 11 | 8 | 13 | 36:41 | -5 | 41 |
| 12 |
|
AC Pontisola | 32 | 10 | 11 | 11 | 48:47 | 1 | 41 |
| 13 |
|
Castellanzese | 32 | 10 | 8 | 14 | 39:45 | -6 | 38 |
| 14 |
|
Sona | 32 | 8 | 11 | 13 | 34:46 | -12 | 35 |
| 15 |
|
Real Calepina | 32 | 8 | 10 | 14 | 30:33 | -3 | 34 |
| 16 |
|
Villa d'Almè | 32 | 7 | 11 | 14 | 43:49 | -6 | 32 |
| 17 |
|
Vis Nova Giussano | 32 | 9 | 4 | 19 | 47:60 | -13 | 31 |
| 18 |
|
USD Caravaggio | 32 | 5 | 14 | 13 | 35:53 | -18 | 29 |
| 19 |
|
Olginatese | 32 | 6 | 9 | 17 | 32:49 | -17 | 27 |
| 20 |
|
AC Leon | 32 | 6 | 8 | 18 | 39:74 | -35 | 26 |
| Ascenso | |
| Playoff | |
| Permanencia | |
| Descenso |
