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| 07.11.2021 | 14:30 | Cascina | - | Virtus Flaminia | 1:2 | |
| 14:30 | Foligno Calcio | - | San Donato Tavarnelle | 0:4 | ||
| 14:30 | Follonica Gavorrano | - | SSD Tiferno Lerchi | 1:1 | ||
| 14:30 | Badesse Calcio | - | ASD Cannara | 0:0 | ||
| 14:30 | Montespaccato | - | Pro Livorno Sorgenti | 3:1 | ||
| 14:30 | FC Rieti | - | US Poggibonsi | 2:1 | ||
| 14:30 | AC Sangiovannese | - | US Arezzo | 1:0 | ||
| 14:30 | SC Trestina | - | US Pianese | 1:0 | ||
| 14:30 | Unipomezia Virtus | - | Scandicci Calcio | 1:1 |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
San Donato Tavarnelle | 8 | 6 | 1 | 1 | 25:12 | 13 | 19 |
| 2 |
|
Follonica Gavorrano | 8 | 5 | 2 | 1 | 18:7 | 11 | 17 |
| 3 |
|
US Arezzo | 8 | 5 | 1 | 2 | 15:10 | 5 | 16 |
| 4 |
|
US Poggibonsi | 8 | 5 | 1 | 2 | 11:6 | 5 | 16 |
| 5 |
|
US Pianese | 8 | 4 | 2 | 2 | 14:9 | 5 | 14 |
| 6 |
|
Montespaccato | 8 | 4 | 2 | 2 | 13:8 | 5 | 14 |
| 7 |
|
SSD Tiferno Lerchi | 8 | 3 | 4 | 1 | 9:7 | 2 | 13 |
| 8 |
|
Virtus Flaminia | 8 | 3 | 2 | 3 | 13:13 | 0 | 11 |
| 9 |
|
SC Trestina | 8 | 3 | 1 | 4 | 9:8 | 1 | 10 |
| 10 |
|
Badesse Calcio | 8 | 2 | 4 | 2 | 6:8 | -2 | 10 |
| 11 |
|
Scandicci Calcio | 8 | 2 | 3 | 3 | 6:8 | -2 | 9 |
| 12 |
|
ASD Cannara | 8 | 1 | 5 | 2 | 6:6 | 0 | 8 |
| 13 |
|
Pro Livorno Sorgenti | 8 | 2 | 2 | 4 | 6:12 | -6 | 8 |
| 14 |
|
FC Rieti | 8 | 2 | 2 | 4 | 10:15 | -5 | 8 |
| 15 |
|
Cascina | 8 | 1 | 4 | 3 | 8:12 | -4 | 7 |
| 16 |
|
AC Sangiovannese | 8 | 1 | 3 | 4 | 8:16 | -8 | 6 |
| 17 |
|
Foligno Calcio | 8 | 1 | 2 | 5 | 8:17 | -9 | 5 |
| 18 |
|
Unipomezia Virtus | 8 | 0 | 3 | 5 | 7:18 | -11 | 3 |
| Ascenso | |
| Playoff | |
| Permanencia | |
| Descenso |
