Cuartos de final
28.04.2021 02:00 Atlanta United FC Atlanta United FC - Philadelphia Union Philadelphia Union -:-
28.04.2021 04:00 Toronto FC Toronto FC - Cruz Azul Cruz Azul -:-
29.04.2021 02:30 Columbus Crew Columbus Crew - CF Monterrey CF Monterrey -:-
29.04.2021 04:30 Portland Timbers Portland Timbers - CF América CF América -:-
05.05.2021 02:00 Philadelphia Union Philadelphia Union - Atlanta United FC Atlanta United FC -:-
05.05.2021 04:15 Cruz Azul Cruz Azul - Toronto FC Toronto FC -:-
06.05.2021 02:00 CF Monterrey CF Monterrey - Columbus Crew Columbus Crew -:-
06.05.2021 04:15 CF América CF América - Portland Timbers Portland Timbers -:-
Semifinales
11.08.2021 N.N.  N.N. - N.N. N.N. -:-
25.08.2021 N.N. N.N. -  N.N. N.N. -:-