| 7. Jornada | 11.09.2021 | FK Senica | - | FK Pohronie | 1:0 | ||||
| 8. Jornada | 18.09.2021 | Tatran Liptovský Mikuláš | - | FK Pohronie | 5:1 | ||||
| 9. Jornada | 24.09.2021 | FK Pohronie | - | AS Trenčín | 2:2 | ||||
| 10. Jornada | 03.10.2021 | Slovan Bratislava | - | FK Pohronie | 5:1 |  |
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| 11. Jornada | 16.10.2021 | FK Pohronie | - | MFK Ružomberok | 2:2 | ||||
| 12. Jornada | 23.10.2021 | FK Pohronie | - | Spartak Trnava | 0:2 | ||||
| 13. Jornada | 30.10.2021 | MFK Zemplín Michalovce | - | FK Pohronie | 0:2 | ||||
| 15. Jornada | 20.11.2021 | ŠKF Sereď | - | FK Pohronie | 3:1 | ||||
| 20. Jornada | 12.02.2022 | AS Trenčín | - | FK Pohronie | 3:0 |
Grecia