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| 28.11.2010 | 11:00 | SpVgg Erkenschwick | - | MSV Duisburg | 0:2 (0:1) | |
| 11:00 | Bor. Mönchengladbach | - | VfL Bochum | 0:1 (0:0) | ||
| 11:00 | Wuppertaler SV | - | Bayer Leverkusen | 1:4 (1:2) | ||
| 11:00 | Borussia Dortmund | - | Arminia Bielefeld | 0:4 (0:1) | ||
| 11:00 | SG Wattenscheid 09 | - | Fortuna Düsseldorf | 1:1 (0:0) | ||
| 12:00 | Schalke | - | Bonner SC | 5:1 (3:0) | ||
| 13:00 | Rot Weiss Ahlen | - | Colonia | 3:3 (1:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta | 1.ª parte | 2.ª parte |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Bayer Leverkusen | 12 | 11 | 0 | 1 | 43:11 | 32 | 33 |
| 2 |
|
Schalke | 12 | 10 | 2 | 0 | 34:8 | 26 | 32 |
| 3 |
|
Bor. Mönchengladbach | 12 | 7 | 2 | 3 | 24:15 | 9 | 23 |
| 4 |
|
MSV Duisburg | 12 | 6 | 1 | 5 | 23:21 | 2 | 19 |
| 5 |
|
Arminia Bielefeld | 12 | 5 | 3 | 4 | 29:21 | 8 | 18 |
| 6 |
|
Fortuna Düsseldorf | 12 | 4 | 5 | 3 | 15:14 | 1 | 17 |
| 7 |
|
Rot Weiss Ahlen | 12 | 5 | 2 | 5 | 24:26 | -2 | 17 |
| 8 |
|
VfL Bochum | 12 | 4 | 2 | 6 | 14:16 | -2 | 14 |
| 9 |
|
Colonia | 12 | 4 | 2 | 6 | 24:27 | -3 | 14 |
| 10 |
|
Borussia Dortmund | 12 | 4 | 2 | 6 | 20:28 | -8 | 14 |
| 11 |
|
Bonner SC | 12 | 3 | 5 | 4 | 15:25 | -10 | 14 |
| 12 |
|
Wuppertaler SV | 12 | 3 | 3 | 6 | 14:25 | -11 | 12 |
| 13 |
|
SG Wattenscheid 09 | 12 | 0 | 4 | 8 | 13:36 | -23 | 4 |
| 14 |
|
SpVgg Erkenschwick | 12 | 0 | 3 | 9 | 9:28 | -19 | 3 |
| Playoff | |
| Descenso |
