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| 03.12.2021 | 19:30 | SV Bergisch Gladbach 09 | - | Fortuna Köln II | 2:1 (2:1) | |
| 05.12.2021 | 14:30 | Viktoria Arnoldsweiler | - | SV Deutz 05 | 4:0 (1:0) | |
| 14:30 | Spvg Wesseling-Urfeld | - | FC Pesch 1956 | 0:4 (0:1) | ||
| 14:30 | SV Breinig | - | BC Viktoria Glesch-Paffendorf | 1:4 (0:1) | ||
| 14:30 | Borussia Freialdenhoven | - | FC Hürth | 1:1 (0:0) | ||
| 15:00 | Siegburger SV 04 | - | VfL Alfter | 2:0 (0:0) | ||
| 15:00 | SpVg Frechen 20 | - | VfL 08 Vichttal | 6:1 (3:0) | ||
| 15:00 | SV 1914 Eilendorf | - | 1. FC Düren | 0:2 (0:1) | ||
| 09.06.2022 | 19:30 | Blau-Weiß Friesdorf | - | FC Hennef 05 | 2:1 (2:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Düren | 17 | 13 | 3 | 1 | 47:11 | 36 | 42 |
| 2 |
|
FC Hennef 05 | 17 | 12 | 3 | 2 | 41:12 | 29 | 39 |
| 3 |
|
SV Bergisch Gladbach 09 | 17 | 11 | 4 | 2 | 44:11 | 33 | 37 |
| 4 |
|
SpVg Frechen 20 | 17 | 11 | 3 | 3 | 39:16 | 23 | 36 |
| 5 |
|
Siegburger SV 04 | 17 | 9 | 5 | 3 | 32:18 | 14 | 32 |
| 6 |
|
Borussia Freialdenhoven | 17 | 9 | 2 | 6 | 29:24 | 5 | 29 |
| 7 |
|
Viktoria Arnoldsweiler | 17 | 9 | 1 | 7 | 32:23 | 9 | 28 |
| 8 |
|
FC Pesch 1956 | 17 | 7 | 6 | 4 | 36:20 | 16 | 27 |
| 9 |
|
BC Viktoria Glesch-Paffendorf | 17 | 7 | 4 | 6 | 31:21 | 10 | 25 |
| 10 |
|
VfL 08 Vichttal | 17 | 7 | 3 | 7 | 33:35 | -2 | 24 |
| 11 |
|
VfL Alfter | 17 | 7 | 3 | 7 | 24:32 | -8 | 24 |
| 12 |
|
Blau-Weiß Friesdorf | 17 | 6 | 5 | 6 | 26:30 | -4 | 23 |
| 13 |
|
FC Hürth | 17 | 6 | 3 | 8 | 24:35 | -11 | 21 |
| 14 |
|
SV 1914 Eilendorf | 17 | 3 | 2 | 12 | 14:38 | -24 | 11 |
| 15 |
|
Fortuna Köln II | 17 | 2 | 4 | 11 | 18:37 | -19 | 10 |
| 16 |
|
Spvg Wesseling-Urfeld | 17 | 3 | 0 | 14 | 16:57 | -41 | 9 |
| 17 |
|
SV Deutz 05 | 17 | 2 | 2 | 13 | 14:43 | -29 | 8 |
| 18 |
|
SV Breinig | 17 | 2 | 1 | 14 | 17:54 | -37 | 7 |
| Playoff | |
| Descenso |
