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| 19.02.2022 | 13:00 | RSV Eintracht 1949 | - | MSV Pampow | 2:2 (1:2) | |
| 20.02.2022 | 13:30 | CFC Hertha 06 | - | TSG Neustrelitz | 0:1 (0:0) | |
| 13:30 | Eintracht Mahlsdorf | - | MSV 1919 Neuruppin | 2:0 (1:0) | ||
| 13:30 | SC Staaken | - | Rostocker FC | 3:2 (0:2) | ||
| 13:30 | Victoria Seelow | - | 1. FC Lok Stendal | 2:2 (0:0) | ||
| 13:30 | Torgelower FC Greif | - | SFC Stern 1900 | 1:1 (0:1) | ||
| 14:00 | Hertha Zehlendorf | - | Hansa Rostock II | 2:0 (1:0) | ||
| 26.03.2022 | 14:00 | Ludwigsfelder FC | - | Blau-Weiß 90 Berlin | 2:3 (0:3) | |
| 17.04.2022 | 14:00 | Brandenburger SC Süd | - | Greifswalder FC | 0:2 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | ∅ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Rostocker FC | 16 | 12 | 0 | 4 | 46:13 | 33 | 36 | 2.25 |
| 2 |
|
Blau-Weiß 90 Berlin | 16 | 11 | 1 | 4 | 35:19 | 16 | 34 | 2.13 |
| 3 |
|
CFC Hertha 06 | 17 | 10 | 4 | 3 | 29:16 | 13 | 34 | 2.00 |
| 4 |
|
SC Staaken | 16 | 9 | 4 | 3 | 32:16 | 16 | 31 | 1.94 |
| 5 |
|
Greifswalder FC | 16 | 9 | 4 | 3 | 28:19 | 9 | 31 | 1.94 |
| 6 |
|
Torgelower FC Greif | 16 | 8 | 4 | 4 | 41:18 | 23 | 28 | 1.75 |
| 7 |
|
Hertha Zehlendorf | 16 | 9 | 1 | 6 | 30:19 | 11 | 28 | 1.75 |
| 8 |
|
RSV Eintracht 1949 | 16 | 7 | 6 | 3 | 28:22 | 6 | 27 | 1.69 |
| 9 |
|
TSG Neustrelitz | 16 | 7 | 5 | 4 | 19:15 | 4 | 26 | 1.63 |
| 10 |
|
MSV Pampow | 16 | 6 | 4 | 6 | 24:30 | -6 | 22 | 1.38 |
| 11 |
|
Eintracht Mahlsdorf | 16 | 6 | 3 | 7 | 24:23 | 1 | 21 | 1.31 |
| 12 |
|
FC Mecklenburg Schwerin | 16 | 6 | 3 | 7 | 24:26 | -2 | 21 | 1.31 |
| 13 |
|
Hansa Rostock II | 16 | 5 | 5 | 6 | 28:29 | -1 | 20 | 1.25 |
| 14 |
|
Ludwigsfelder FC | 16 | 5 | 2 | 9 | 19:31 | -12 | 17 | 1.06 |
| 15 |
|
MSV 1919 Neuruppin | 16 | 3 | 4 | 9 | 18:36 | -18 | 13 | 0.81 |
| 16 |
|
Victoria Seelow | 16 | 3 | 3 | 10 | 17:40 | -23 | 12 | 0.75 |
| 17 |
|
1. FC Lok Stendal | 16 | 3 | 3 | 10 | 20:45 | -25 | 12 | 0.75 |
| 18 |
|
Brandenburger SC Süd | 17 | 2 | 3 | 12 | 11:31 | -20 | 9 | 0.53 |
| 19 |
|
SFC Stern 1900 | 16 | 0 | 5 | 11 | 16:41 | -25 | 5 | 0.31 |
| Ascenso | |
| Permanencia | |
| Descenso |
