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| I | Milan | - | Tottenham Hotspur | 0:1 (0:0) | ||
| V | Tottenham Hotspur | - | Milan | 0:0 (0:0) | ||
| I: 15.02.2011 20:45 | V: 09.03.2011 20:45 | Campeones: Tottenham Hotspur | ||||
| I | Valencia | - | Schalke | 1:1 (1:0) | ||
| V | Schalke | - | Valencia | 3:1 (1:1) | ||
| I: 15.02.2011 20:45 | V: 09.03.2011 20:45 | Campeones: Schalke | ||||
| I | Roma | - | Shakhtar Donetsk | 2:3 (1:3) | ||
| V | Shakhtar Donetsk | - | Roma | 3:0 (1:0) | ||
| I: 16.02.2011 20:45 | V: 08.03.2011 20:45 | Campeones: Shakhtar Donetsk | ||||
| I | Arsenal | - | Barcelona | 2:1 (0:1) | ||
| V | Barcelona | - | Arsenal | 3:1 (1:0) | ||
| I: 16.02.2011 20:45 | V: 08.03.2011 20:45 | Campeones: Barcelona | ||||
| I | Lyon | - | Real Madrid | 1:1 (0:0) | ||
| V | Real Madrid | - | Lyon | 3:0 (1:0) | ||
| I: 22.02.2011 20:45 | V: 16.03.2011 20:45 | Campeones: Real Madrid | ||||
| I | FC København | - | Chelsea | 0:2 (0:1) | ||
| V | Chelsea | - | FC København | 0:0 (0:0) | ||
| I: 22.02.2011 20:45 | V: 16.03.2011 20:45 | Campeones: Chelsea | ||||
| I | Inter | - | Bayern Múnich | 0:1 (0:0) | ||
| V | Bayern Múnich | - | Inter | 2:3 (2:1) | ||
| I: 23.02.2011 20:45 | V: 15.03.2011 20:45 | Campeones: Inter | ||||
| I | Marsella | - | Manchester United | 0:0 (0:0) | ||
| V | Manchester United | - | Marsella | 2:1 (1:0) | ||
| I: 23.02.2011 20:45 | V: 15.03.2011 20:45 | Campeones: Manchester United | ||||
